It is well known that pH plays a pivotal role in the control of bone remodeling.However, no comprehensive gene expression data are available for the effects of alkaline pH on osteoblasts.We cultured differentiating MC3T3-E1 osteoblast-like cells at pH 7.4, 7.8, and 8.4 for 14 days.To identify differential gene expression, microarray data were colle
Brief Myocardial Ischemia Produces Cardiac Troponin I Release and Focal Myocyte Apoptosis in the Absence of Pathological Infarction in Swine
Summary: In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue necrosis, we demonstrated delayed release of cardiac troponin I (cTnI) that exceeded the 99th percentile for normal ice cubes chocolate blue wrapper animals 60 min after reperfusion and rose to readily detectable levels 24 h later.Although tissue a